San Francisco 49ers @ New Orleans Saints – The Saints and 49ers have been the class of the NFC over the past couple of seasons, but San Francisco has won their last two against New Orleans, including last season at the Superdome. The Saints are a three-point NFL betting favorite at home.
Kansas City Chiefs @ Denver Broncos – The 9-0 Chiefs head to Denver, where they have lost three of their last five trips, but head coach Andy Reid was 13-1 in Philadelphia after a bye week. This AFC West showdown will light up Sunday night, when the Broncos will be 7.5-point favorites in the sportsbook.
New England Patriots @ Carolina Panthers MNF – The Panthers have won five in a row, but they have lost three of their last five against the Patriots, including the Super Bowl in 2004. Carolina should be a slight home favorite on Monday night.